In addition, within the HMS/EDS-HT phenotype, there is a high prevalence of psychosocial factors, which again presents a difficult issue that needs to be addressed (Challenge 3).
Despite recent scientific advances, many obstacles for clinical care and research still remain.
Both physicians combined the pertinent features of the syndrome and accurately delineated the phenotypic features of this group of inherited disorders.
The name, Ehlers-Danlos syndrome, was coined in 1936.
Some patients with EDS can demonstrate amazing, almost unnatural, contortions, often arousing the curiosity of onlookers.
Niccolo Paganini (1782-1840) the famous Italian violinist, who was capable of miraculous feats in his playing owing to his hypermobile and loose joints, had phenotypic traits of EDS.
Depending on the type, EDS can be diagnosed through laboratory studies or clinical examination.
Once the syndrome has been diagnosed, preventative measures should be taken. Tschernogobow, a Russian dermatologist, presented 2 case studies of patients to the Moscow Venereology and Dermatology Society who had marked loose fragile skin, and hypermobile large joints.
Keywords: chronic musculoskeletal pain, generalized joint hypermobility, hypermobility syndrome, Ehlers–Danlos hypermobility type This work is published and licensed by Dove Medical Press Limited.
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