After pregnancy, diabetes type 1 or 2 may occur and will require obligatory treatment.
Genetic Factors and Markers The role of genetic factors as a cause of diabetes has been proven definitively. IDDM is considered to be a polygenic disease which is based on at least two of the mutant genes in diabetic chromosome 6.
Genetic susceptibility is linked with particular genes of HLA systems, which are considered markers of such a predisposition.
Patients with a genetic predisposition to IDDM have an altered response to environmental factors.
The cause and cure of type 2 diabetes remains unknown; however, genetic factors and manner of living take part in its causes, and watching blood sugar level can control the disease.
Gestational Diabetes Gestational diabetes happens when there is a development of high blood sugar level in pregnant women not previously diagnosed of diabetes.
A crucial point in this step is the expression of B cells HLA-DR-antigen and glutamic acid, and therefore, they become autoantigens that cause the development of autoimmune response reactions.
Third stage – the stage of the active immunological process with formation of antibodies to B cells, insulin and autoimmune insulitis development.
Clinical signs of diabetes form and insulin treatment becomes necessary again.
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